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MICROBIOLOGY AND ITS SPECIAL TECHNIQUES Course Sheet Academic Year of enrolment:
Disciplinary Sector:
Laboratory Medicine Techniques
Professor and Collaborators:
Hours of classroom activity:
Prerequisites:
Those listed in the didactics regulation.
Objectives
Contents The course provides the conceptual basis for understanding pathogenic bacteria and viruses and the mechanisms by which they cause disease in the human body. In particular, classes of microorganisms of specific relevance to the common diseases will be discussed in detail. Identification of each pathogen is emphasized and includes selection of specimens to examine, routes of transmission, isolation media, and macroscopic and microscopic characteristics as applicable. Disease correlation and disease prevention are covered as well.
Extended Syllabus Special Microbiology and related techniques.
Classification of microorganisms.
Pathogenesis, Lab diagnosis, Treatment, Prevention and Control of the bacterial human pathogens.
Gram-positive cocci: Staphylococci, Streptococci. Gram-negative cocci: Neisseria. Gram-positive rods: Mycobacterium, Corynebacterium, Listeria monocytogenes. Gram-negative rods: Enterobacteriaceae, Vibrionaceae, Pseudomonadaceae, Campylobactr, Helicobacter, Bordetella, Brucella. Spore-forming Gram-positive bacilli: Clostridium and Bacillus. Spirochaetes, Mycoplasma, Legionella pneumoniae, Rickettsie, Chlamydiae.
Pathogenesis, Lab diagnosis, Treatment, Prevention and Control of the viral human pathogens.
Characteristics and classification of viruses. Virus structure: non- enveloped and enveloped viruses. Viral replication: life cycle of viruses with animal and prokaryote hosts. Mechanisms of viral pathogenesis. Antiviral drugs.
RNA viruses: Orthomyxovirus, Rotavirus, Filovirus, Retrovirus, Togaviridae, Paramyxoviridae, Flaviviridae, Picornavirus, Delta virus.
DNA viruses: Poxvirus, Herpesvirus, Hepadnavirus, Papillomavirus.
Prions. Hospital-acquired infections.
Recommended Bibliography Antonelli, Clementi, Pozzi, Rossolini: Principi di Microbiologia Medica, 3a Ed., 2017.
Murray PR, Rosenthal KS, Pfaller MA: Microbiologia Medica 8a Ed. Edra, 2017.
Teaching Methods Teaching method: frontal lectures and material provided by teacher.
Evaluation methods Verification of learning:
Oral examamination.
N.B. For Integrated Courses (exams covering more than one module or course unit) a single exam will be held and a final grade given.
Contacts/More Information Prof. Nerino Allocati
In-Person office hours: Monday – Friday from 10:00 to 13:00.
Or by appointment: contact the professor by email: nerino.allocati@unich.it .