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Course Sheet Academic Year of enrolment:
Professor and Collaborators:
Hours of classroom activity:
Prerequisites:
knowledge of cellular and molecular biology, histology and biochemistry, acquired in the curricular courses and the.prerequisites required by the core curriculum of CdS
Objectives
Contents Concept of health, homeostasis, disease and pathogenesis.
Cellular adaptation
Inflammation.
Immunology and Immunopathology
Oncology
Extended Syllabus -General concept of disease, etiology and pathogenesis. Intrinsic and extrinsic causes of disease. Pathology caused by physical (heat, radiation), chemicals (acids and bases) and biological (pathogens) agents.
- Cellular responses to microenvironment change: cellular adaptation, cell death (necrosis and apoptosis)
-Inflammation: acute and chronic inflammation; Granulomas, systemic phenomena of inflammation.
-Healing of tissue lesions: regeneration and repair.
- Immunology and immunopathology of the oral cavity: the organization of the immune system. Natural and acquired immunity: mechanisms of humoral and cellular immunity (antibodies, antigens of the major histocompatibility complex, complement).
Immunopathological reactions: hypersensitivity and autoimmunity
-Oncology: Characteristics of benign and malignant tumor. Definition of oncogenes, and oncosuppressor genes. Chemical carcinogenesis: carcinogens and their cellular interaction, stages of carcinogenesis.Tumor growth biology: growth and differentiation, angiogenesis, progression, invasive growth and metastasis.
Recommended Bibliography Pontieri G.M.: Patologia e Fisiopatologia generale. Edizione Piccin-Piccin Nuova Libraria
Teaching Methods Knowledge will be acquired through single-issue lessons. The slides of the lessons are made available to the student. The learning of some issues can also be implemented by consulting texts provided by the teacher
Discussion in the classroom solicited by the teacher aimed at understanding the topics dealt with and the management of doubts and perplexities on the information acquired.
Teacher-student interaction: by appointment via email
Evaluation methods Verification of learning:
The learning evaluation will be done by oral examination. It consists of an interview with the teacher. The topics of the interview will be listed in the Extended Syllabus Program. The interview is aimed at evaluating the student in the knowledge of the main concepts represented in the objectives of the course; in the ability to use appropriate medical and scientific terminology; in the ability of critical synthesis of the topics also by the deepening in the recommended texts.
Contacts/More Information the partecipation to the lessons and the acquisition of the frequency signature is mandatory for the final exam, in compliance with the prerequisites.
The teachers are available for clarification to the students, from monday to friday 10.00 - 13.00
Nuovo Polo Didattico, Palazzina C, III livello.
Dip.to di Scienze Mediche, Orali e Biotecnologiche, sez. di Immunodiagnostica tel. 0871.3554029
E-mail: mreale@unich.it ,
for appointment.