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Course Sheet Academic Year of enrolment:
Disciplinary Sector:
Microbiology and Clinical Microbiology
Professor and Collaborators:
Hours of classroom activity:
Prerequisites:
Those listed in the didactics regulation.
Objectives
Contents The subject covers mechanisms of infectious disease transmission and pathogenicity. The course provides the conceptual basis for understanding pathogenic microorganisms and viruses, and the mechanisms by which they cause disease in the human body. In particular, classes of microorganisms of specific relevance to the common oral diseases will be discussed in detail.
Extended Syllabus Mechanisms of bacterial pathogenesis: entry into the human body; adhesion, colonization and invasion; pathogenic actions of bacteria (tissue destruction, toxins); mechanisms for escaping host defenses.
Antibacterials and their mechanisms of action. Mechanisms of drug resistance.
Gram-positive cocci: Staphylococci, Streptococci. Gram-negative cocci: Neisseria. Gram-positive rods: Mycobacterium, Actinomyces. Gram-negative rods: Enterobacteriaceae, Vibrionaceae, Campylobacter, Helicobacter. Spore-forming Gram-positive bacilli: Clostridium and Bacillus. Anaerobic bacteria in oral cavity. Spirochaetes.
RNA viruses: Orthomyxovirus, Rotavirus, Filovirus, Retrovirus, Coronavirus, Flavivirus, Picornavirus, Delta virus. DNA viruses: Poxvirus, Herpesvirus, Hepadnavirus, Papillomavirus. Antiviral drugs.
Prions.
Hospital-acquired infection.
Oral bacterial diseases: dental caries, periodontal diseases, peri-implantitis, dental abscess, pulpitis and dental pulp necrosis. Oral fungal and viral infections. Antimicrobial prophylaxis.
Selection, collection procedure, storage, transport and processing of clinical specimens.
Culture: use of non-selective and selective media.
Microbial Identification: conventional and molecular methods.
Disinfection and sterilization, and dental asepsis.
Recommended Bibliography E. Lanciotti: Microbiologia Clinica, CEA - Quarta Ed. 2017.
Murray PR, Rosenthal KS, Pfaller MA: Microbiologia Medica 8a Ed. Edra, 2017.
La Placa: Principi di Microbiologia Medica, EdiSES - Ed. XIV 2014
Teaching Methods Teaching method: frontal lectures and material provided by the teacher.
Evaluation methods Verification of learning:
Oral examination.
N.B. For Integrated Courses (exams covering more than one module or course unit) a single exam will be held and a final grade given.
Contacts/More Information In-Person office hours: Monday – Friday from 10:00 to 13:00.
Or by appointment: Contact the professor by email: nerino.allocati@unich.it .