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Course Sheet Academic Year of enrolment:
Disciplinary Sector:
Microbiology and Clinical Microbiology
Professor and Collaborators:
Hours of classroom activity:
Prerequisites:
Those listed in the didactics regulation.
Objectives
Contents The course covers basic principles of general microbiology. Topics include bacterial, viral, and fungal structure, as well as growth, physiology, genetics and biochemistry of microorganisms.
The subject also describes the complexity of the resident oral microbiota, and the mouth as a microbial habitat.
Extended Syllabus Difference between Prokaryotic and Eukaryotic cells.
Naming and Classifying Microorganisms.
The bacterial cell: Size, shape and arrangements of bacteria.
Structures external to the cell wall: glycocalyx, flagella, pili and fimbriae.
The cell wall: composition and characteristics; cell wall and Gram stain; atypical cell walls.
Structures internal to the cell wall: the plasma membrane; the cytoplasm; the nucleoid; plasmids and resistance factors; ribosomes.
Bacterial metabolism: aerobic respiration; anaerobic respiration and fermentation.
Bacterial division and generation time.
Bacterial spore: structure, types, sporulation and germination, and their protecting role in biocide resistance.
Biology of Fungi: general characteristics, structure and classification. Fungal pathogenesis.
Characteristics and classification of viruses.
Virus structure: non-enveloped and enveloped viruses.
Viral replication: life cycle of viruses with animal and prokaryote hosts.
The resident oral microbiota. The mouth as a microbial habitat. Dental plaque: microbial biofilms in the mouth; mechanism of dental plaque formation.
Recommended Bibliography E. Lanciotti: Microbiologia Clinica, CEA - Quarta Ed. 2017.
Murray PR, Rosenthal KS, Pfaller MA: Microbiologia Medica 8a Ed. Edra, 2017.
La Placa: Principi di Microbiologia Medica, EdiSES - Ed. XIV 2014
Teaching Methods Frontal lectures and material provided by the teacher.
Evaluation methods Verification of learning:
Oral examination.
N.B. For Integrated Courses (exams covering more than one module or course unit) a single exam will be held and a final grade given.
Contacts/More Information In-Person office hours: Monday – Friday from 10:00 to 13:00.
Or by appointment: Contact the professor by email: nerino.allocati@unich.it .