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PHARMACOLOGY AND THERAPEUTICS Course Sheet Academic Year of enrolment:
Degree:
Course of 1st Cycle Degree in NURSING
Professor and Collaborators:
Hours of classroom activity:
Prerequisites:
The student must have basic knowledge of biology, biochemistry, anatomy and physiology.
Objectives
Contents The course includes two sections:
1) General pharmacology: this section describes the principles that underlie the human-drug interactions and that in turn are divided into two chapters, one related to Pharmacokinetics (the effects that the body has on drugs) and the other one on Pharmacodynamics (the cellular and molecular mechanisms that underlie the therapeutic, unwanted and toxic effects of drugs).
2) Special Pharmacology and therapy: this section describes the characteristics of the single classes of drugs (in particular those of the most common use in hospital settings).
Extended Syllabus PRINCIPLES OF GENERAL PHARMACOLOGY: definition of drug; generic drugs and medicinal specialties; overview of pharmacovigilance.
Pharmacokinetic elements: main routes of drug administration (outline of the main pharmaceutical forms and the correct administration of drugs); absorption, distribution, biotransformation and excretion of drugs; bioavailability; therapeutic range; plasma half-life; dose-effect curves (DE50, DL50, DT50); therapeutic index.
Principles of pharmacogenetics and variability of the pharmacological response.
Elements of Pharmacodynamics: drug-receptor interactions; main receptor classes; main signal transduction pathways; receptor agonists and antagonists; definition of power and maximum efficacy of a drug; receptor desensitization, upregulation, and downregulation.
PRINCIPLES OF SPECIAL PHARMACOLOGY
Pharmacological therapy of inflammation. Glucocorticoids and non-steroidal anti-inflammatory drugs (NSAIDs).
Drugs used in the treatment of bronchial asthma (essential lines on the most common drugs).
Drugs of more common use for the control of gastric acidity and for the treatment of peptic ulcer.
Drugs used in the treatment of bronchial arterial hypertension (essential lines on drugs of most common use).
Drugs used in the treatment of bronchial heart failure (essential lines on drugs of most common use).
Drugs active on the central nervous system with particular reference to the use of benzodiazepines
Antibacterial chemotherapy: Classification of antimicrobial drugs. Factors that determine the susceptibility and resistance of microorganisms to the most common antimicrobial drugs (Penicillins, Cephalosporins, Macrolides, Fluoroquinolones).
Recommended Bibliography The recommended texts are:
Farmacologia -H.P. Rang, M.M. Dale, J.M. Ritter, P.K. Moore, Casa Editrice Ambrosiana, (ultima edizione).
For further information:“Fondamenti di farmacologia per infermieri” Clayton, Stock (ultima edizione)
Any additional materials will be made available by the teacher to supplement the recommended texts and uploaded to the dedicated website.
Teaching Methods The teaching is divided into lectures whose purpose is to transmit concepts, information and schemes.
Evaluation methods Verification of learning:
The student must register for the examination session on Esse3. The level of learning related to the module of Pharmacology and Therapy takes place in oral form. In the absence if the teacher, it will be in written form with multiple choice questions (each question has 4 answers, of which only one is correct) involving the areas of general pharmacology and special pharmacology reported in the program.
The test must be completed within 30 minutes. The written test of Pharmacology and Therapy is carried out before the examination tests related to the other modules of the Integrated Course.
The final grade is calculated as a weighted average on the credits of the individual modules of the positive results (above 18/30) of the different modules of the integrated course.
The exam mode and the evaluation method are indicated by the teacher at the beginning of the lessons.
Contacts/More Information I meet students each friday from 10am to 12 am at CesiMET (0871541471)