Error message
User error : Failed to connect to memcache server: druportbe01:11211 in dmemcache_object() (line 415 of /production/drupal/dim_prod/drupal/d7cl4/prod/unich/releases/7/web/sites/all/modules/contrib/memcache/dmemcache.inc ).
PHYSIOPATHOLOGY OF THE ORAL CAVITY Integrated educational activity
Course Sheet Academic Year of enrolment:
Hours of classroom activity:
Prerequisites:
Anatomical knowledge of the cardiovascular and respiratory systems and of the oral cavity and of the main biochemical processes underlying cellular metabolisms, , in order to understand the physiological processes
Objectives
Contents Excitable tissues and potentials . Synapses. Neurotransmitters.
Hematopoietic organs and tissues. Physiology of blood coagulation. Cardiovascular and respiratory systems.
Special part:
Salivary gland functions. Physiology and intraoral defense mechanisms. Sensory perception of the orofacial territory. Trigeminal nerve. The dental pulp. Chewing. The temporomandibular joint (ATM).
Concept of health, homeostasis, disease and pathogenesis.
Cellular adaptation
Inflammation.
Immunology and Immunopathology
Oncology
Extended Syllabus Excitable tissues. Rest potential, depolarization and hyperpolarization. Action potential. The cells of the nervous system. The neuron. Classification of nerve fibers. Propagation of action potential. Synapses. Neurotransmitters.
Hematopoietic organs and tissues. Red blood cells, white blood cells, platelets: their functions. The physiology of primary hemostasis. Emocoagulation factors and physiology of blood coagulation. Cardiovascular and respiratory systems.
Special part.
Salivary glands: innervation of the main salivary glands, stimuli to the secretion. Physiology and intraoral defense mechanisms. Sensory perception of the orofacial territory: mechanoception, nociception, thermoception. Taste. Anatomical and functional organization of the trigeminal system. Trigeminal sensitivity, trigeminal pain. The dental pulp: function of the pulp nerves, nociceptive response. Mastication: chewing muscles and chewing mechanics. The temporomandibular joint (TMJ) and its innervation.
-General etiology: concept of disease, etiology and pathogenesis. The causes of diseases such as alterations of organs and tissues. Intrinsic and extrinsic causes of disease. Environmental pathology: pathology caused by physical agents (heat, radiation), chemicals (acids and bases) and biological (pathogens) of the oral cavity.
- Cellular responses to microenvironment change: cellular adaptation
-Inflammation: acute inflammation; chronic inflammation; Granulomas, systemic phenomena of inflammation, fever.
-Healing of tissue lesions: regeneration and repair.
- Immunology and immunopathology of the oral cavity: the organization of the immune system. Natural and acquired immunity: mechanisms of humoral and cellular immunity (antibodies, antigens of the major histocompatibility complex, complement).
Immunopathological reactions: hypersensitivity and autoimmunity
-Oncology: Characteristics of benign and malignant tumor. Definition of oncogenes, and oncosuppressor genes. Tumor growth biology: growth and differentiation, angiogenesis, progression, invasive growth and metastasis.
Chemical carcinogenesis: carcinogens and their cellular interaction, phases of carcinogenesis.
Recommended Bibliography Fisiologia Umana - Sherwood- Zanichelli
o Fisiologia Monticelli II ed CEA
Fisiologia Orale e dell'Apparato Stomatognatico
- Diego Manzoni - Eugenio Scarnati- Edi-Ermes
Pontieri G.M.: Patologia e Fisiopatologia generale. Edizione Piccin-Piccin Nuova Libraria
Teaching Methods
Evaluation methods Verification of learning:
The learning evaluation will be done by oral examination. It consists of an interview with the teacher. The topics of the interview will be listed in the Extended Syllabus Program. The interview is aimed at evaluating the student in the knowledge of the main concepts represented in the objectives of the course; in the ability to use appropriate medical and scientific terminology; in the ability of critical synthesis of the topics also by the deepening in the recommended texts.The oral examination of physiology takes place with at least one question on the apparatus and one question on the special part
Contacts/More Information The partecipation to the lessons and the acquisition of the frequency signature is mandatory for the final exam, in compliance with the prerequisites.
The General pathology teacher is available for clarification to the students, from monday to friday 10.00 - 13.00
Nuovo Polo Didattico, Palazzina C, III livello.
Dip.to di Scienze Mediche, Orali e Biotecnologiche, sez. di Immunodiagnostica tel. 0871.3554029
E-mail: mreale@unich.it ,
for appointment.
Student reception
The Physiology teacher receives the students on Tuesday from 4:00 pm to 6:00 pm and on Wednesday from 11.00 am to 1.00 pm at the Cellular Physiology Laboratory of the Department of Neuroscience Imaging and Clinical Sciences (New buildings of Pharmacy Body A 2nd level).