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MICROBIOLOGY, PHARMACOLOGY AND HYGIENE Integrated educational activity
Course Sheet Academic Year of enrolment:
Hours of classroom activity:
Prerequisites:
As stated by academic rules
Objectives
Contents The Integrated Course of Microbiology, Pharmacology, Hygiene is composed of the following courses: Pharmacology, Microbiology and clinical Microbiology, Hygiene
Extended Syllabus Shape and structure of the bacterial cell
• Bacterial reproduction and spore production
• Microbial growth and culture media
• Pathogenic action of bacteria
• Antimicrobial agents
Structure of the fungal cell
• metabolism and reproduction
• Pathogenic action of fungi
• Antifungal drugs
Notes on Protozoa
Structure and classification of viruses
• Cultivation and titration of viruses
• Pathogenic action of viruses
• Antiviral drugs
Physical and chemical agents in the control of microorganisms
Hospital infections
- Introduction to Pharmacokinetics: absorption, distribution, metabolism, elimination.
- Introduction to Pharmacodynamics: receptor, receptor signal transduction mechanisms, agonist and antagonist concept, potency and efficacy of a drug, therapeutic index
- Rational principles of radiopharmaceutical therapy
-Classification of immune-mediated reactions to drugs and contrast media.
- Reactions to contrast media[examples of premedication and therapy (Pharmacology of histaminergic transmission and cortisonic drugs)]
General principles of epidemiology and prevention
- Main epidemiological measures (prevalence, incidence, relative risk)
- Basis of the main epidemiological studies
Epidemiology of infectious diseases
- Microbial agents
- Natural history of infectious diseases
- Determinants of infectious diseases
- Transmission mode
- Spatio-temporal relationships in the infectious diseases spread
General prophylaxis of infectious diseases
- Indirect prophylaxis: generality and areas of intervention
- Direct prophylaxis: principles, methods for sterilization, disinfection and disinfestation
- Specific prophylaxis: vaccines, immune sera, immunoglobulins, vaccination calendar, chemoprophylaxis
Etiology, epidemiology and prophylaxis of the following diseases:
- Viral hepatitis (A, B, C, notes on the others)
- Acquired Immuno Deficiency Syndrome (AIDS)
- Tetanus
- Influenza
- Food infections
Recommended Bibliography E. Lanciotti: Principi di Microbiologia Clinica, CEA
La Placa: Principi di Microbiologia Medica, Esculapio
F. Clementi e G. Fumagalli. Farmacologia generale e molecolare. Editore:UTET
Panus PC, Katzung B, Jobst EE, Tinsley SL, Masters SB, Trevor AJ. Farmacologia in riabilitazione, Edi-ermes
Meloni C. Igiene per le lauree delle professioni sanitarie. Casa Editrice Ambrosiana; additional teaching material: slide projected in class and provided by the teacher
Teaching Methods Within the microbiology course, the theoretical knowledge will be acquired through the attendance to the lessons, integrated with the study of the recommended textbooks and the material provided by the teacher in the classroom.
The course of pharmacology includes lectures and interactive lessons. It aims to provide the theoretical basis necessary for a reasoned understanding of what the drug produces once it has been introduced into the human organism (pharmacodynamics) taking into account how it is distributed and modified in the organism itself (pharmacokinetics). At the same time, special care will be taken in linking theoretical knowledge with the evidence emerging from the use of drugs as tools of therapeutic armamentarium. In itinere will be proposed exercises (multiple choice tests) to verify the level of personal learning on the various covered topics.
The course of hygiene is structured in lectures that provide a strong interactive component between Teacher and Students. The course is divided into three phases that are preliminary to each other. The aim of the first phase is to provide the conceptual basis of the epidemiological discipline, its generic and specific rationale for its application in the prevention of infectious diseases. The second training objective is to provide the student with an overview of the main epidemiological methodologies. The central core of the course, however, is represented by the third phase that provided basic knowledge on the dissemination, transmission and prevention methods of the main infectious diseases, that are of considerable importance for the future professional activity.
Evaluation methods Verification of learning:
Oral exam
The Integrated Course examination consists of a single exam, including all disciplines, always to be taken in the same examination session
The evaluation will be carried out using marks out of thirty.
Contacts/More Information Please refer to the individual scheme