1. Mitosis, meiosis and cell cycle.2. nucleic acid structures; genetic transmission through cell division; DNA duplication; DNA repair processes.3. DNA organization within cell compartments; mitochondrial DNA structure and organization. Eukaryote gene structure and functional organization; eukaryote/prokaryote DNA structure variations. Genetic code structure and its decode. Regulation in gene expression and messenger RNA splicing.4. Gene mutations, recombination and transposon activities.5. Mendelian monogenic inheritance, genotype/phenotype correlation, sex chromosome linked genes. Mendel law exceptions, gene linkage, multifactorial inheritance.6. Chromatin structure and function, gene families and genetic polymorphisms.7. Standard human karyotype. Sex chromosomes and determination of sex features. Genomic and chromosomal mutations. Chromosomal fragile sites. Chromosome banding and molecular cytogenetics.8. Hemoglobin structures and their alterations.9. Imprinting, its regulation and alterations.10. Main molecular approaches for DNA analysis and its manipulation including genetic engineering.