APPLIED MEDICAL SCIENCES AND TECHNIQUES III

Università degli Studi
"G. d'Annunzio"

Chieti - Pescara

General Module

Course Sheet

Course code:

TF22B5A

Academic Year of enrolment:

2021

Year of supply:

2022/2023

Type of Course:

Characterising

Degree:

Course of 1st Cycle Degree in CARDIOCIRCULATORY AND CARDIOVASCULAR PERFUSION TECHNIQUES

Disciplinary Sector:

Applied Medical Sciences

Is part of:

INTRODUCTION TO CARDIAC SURGERY TECHNIQUE I

Location:

CHIETI

Credits:

Programme Year:

Professor and Collaborators:

DI PIETRO NATALIA

Cycle:

First semester

Obligatory attendance:

Yes

Hours of classroom activity:

Individual study hours:

Prerequisites:

none

Objectives

The student will have to acquire the knowledge related to the operation and management of the heart-lung machine during the CBP. Furthermore, you will have to acquire the knowledge related to the pathophysiological aspects of the CBP.

Contents

The course includes a description of the various components of the heart-lung machine, retracing the history of the development of the current components. Furthermore, the main monitoring and protocols (priming, hemodilution, hypothermia, cardioplegia) used during the cardio-pulmonary bypass (CBP) will be described. To this end, and to facilitate the student, some concepts relating to the anatomy and physiology of the cardiovascular system will be recalled with particular attention to the main mechanisms underlying vascular alterations: endothelial function / dysfunction and role of nitric oxide (NO).

Extended Syllabus

1. References to the main themes of anatomy and physiology of the cardiovascular system (HEART)
2. References to the main themes of anatomy and physiology of the cardiovascular system (BLOOD VESSELS)
3. Endothelium and its functions in vascular homeostasis: role of Nitric Oxide (NO)
Endothelial dysfunction and atherosclerosis: role of oxidative stress and inflammation
4. Mechanisms underlying the development of vascular complications in various diseases, such as: hypertension, insulin resistance, diabetes, obesity and uremia. Evaluation of endothelial function: classical methods and development of new biomarkers
5. Cardiopulmonary Bypass (CPB): history
6. CPB: materials and devices
7. CPB: preparation of patients
8. CPB: Priming and Cardioplegia
9. Monitoring during CPB
10. CPB: hypothermia
11. CPB: acid-base balance
12. Outline on CPB weaning and arrest.
As part of the discussion of the various topics, gender differences will be addressed.

Recommended Bibliography

The student will be provided with slides relating to the lessons, accompanied by articles and reviews of the literature relating to the topics covered.
However, during the three-year course of the MED / 50 discipline, students could consider the following texts:
- Glenn P. Gravlee, Richard F Davis, Alfred H. Stammeres, Ross M. Ungerleide
Cardiopulmonary Bypass - Principle and Practice
3rd edition
Ed Lippincott Williams and Wilkins
- Glenn P. Gravlee, Richard F. Davis John Hammon, Barry Kussman
Cardiopulmonary Bypass and Mechanical Support - Principle and Practice
4th edition
Ed Lippincott Williams and Wilkins
- Albert C. Perrino, Florian Falter, Sunit Ghosh
Cardiopulmonary Bypass
2nd edition
Ed: Cambridge University Press

Teaching Methods

The course will consist of lectures.

Evaluation methods

Verification of learning:

The final exam consists of an oral test.

Contacts/More Information

During the lesson, the teacher will provide the contact details to be contacted.

Università degli Studi
"G. d'Annunzio"

Chieti - Pescara

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