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Course Sheet Academic Year of enrolment:
Degree:
Course of Single Cycle Degree 5 years in PHARMACY
Disciplinary Sector:
Applied Technological Pharmaceutics
Professor and Collaborators:
Minimum hours of attendance:
Hours of classroom activity:
Prerequisites:
Pharmaceutical Technology with laboratory
Objectives
Contents FUNDAMENTALS OF DRUG DELIVERY SYSTEMS:
Introduction to drug delivery systems and nanomedicine.
DRUG DELIVERY SYSTEMS:
Fundamentals: Differences between drug delivery systems and conventional drug dosage form. Mechanisms of diffusion and transport of drugs modulated by drug delivery systems. Biopharmaceutical and technological properties of drug delivery systems. Biomaterials in drug delivery. Passive and active targeting. Lipid and polymeric drug delivery systems. Nanometric implantable devices.
Examples of drug delivery systems: Lipid drug delivery systems (Doxil/Caelyx). Polymeric drug delivery systems (Abraxane). Nanochannel biomedical devices (nDS).
Extended Syllabus FUNDAMENTALS OF DRUG DELIVERY SYSTEMS:
Introduction to drug delivery systems and nanomedicine.
DRUG DELIVERY SYSTEMS:
Fundamentals: Differences between drug delivery systems and conventional drug dosage form. Mechanisms of diffusion and transport of drugs modulated by drug delivery systems. Biopharmaceutical and technological properties of drug delivery systems. Biomaterials in drug delivery. Passive and active targeting. Lipid and polymeric drug delivery systems. Nanometric implantable devices.
Examples of drug delivery systems: Lipid drug delivery systems (Doxil/Caelyx). Polymeric drug delivery systems (Abraxane). Nanochannel biomedical devices (nDS).
Recommended Bibliography COLOMBO P., CATELLANI P.L., GAZZANIGA A., MENEGATTI E., VIDALE E., Principi di tecnologie farmaceutiche, Ambrosiana, Milano, Ultima edizione. AULTON Tecnologie Farmaceutiche, Progettazione e allestimento dei medicinali, Caviglioli G., Coviello T., De Rosa G., Modena T., Ultima edizione. A.T. FLORENCE, D. ATTWOOD Le basi chimico-fisiche della tecnologia farmaceutica. Edises Ultima edizione.
Teaching Methods Classes: 2 h
Individual Training: 2 h
Evaluation methods Verification of learning:
Oral discussion of topics included in the program.
4 different questions, 2 questions for each modules discussing the thematic issues of the program
Minimum score for the approval: 18/30
Contacts/More Information Individual meetings after scheduled appointments and interactive discussion during teaching activities