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Course Sheet Academic Year of enrolment:
Professor and Collaborators:
Hours of classroom activity:
Prerequisites:
Knowledge of Human Anatomy, Physics and Biochemistry. Prerequisites: according to the Teaching Regulations of the Course (Regolamento Didattico)
Objectives
Contents Description of the mechanisms underlying the functional processes at the cellular, organ and apparatus levels. Illustration of the functioning of organs and systems of the human body. Definition of the principles that regulate cellular and sensory transduction, to arrive at the description of the endocrine and nervous systems integration and control of the metabolism.
Extended Syllabus - General principles of endocrine physiology
Homeostasis concept. Hormones: classification, biosynthesis, secretion. Blood transport and binding to plasma proteins, free quota. Circadian rhythms and hormonal secretion.
- Hypothalamic-pituitary axis
Role of the hypothalamus in the control of hormonal secretion. Hypothalamic neuroendocrine cells. Functional aspects of the pituitary portal circle. Neurohypophysis hormones: oxytocin and vasopressin. Adenohypophysis. Endocrine growth regulation (GH). Prolactin. Hypothalamic-pituitary-thyroid axis: TSH, thyroid hormones T3 and T4. Hypothalamic-pituitary-adrenal axis, ACTH, cortisol, aldosteone, dehydroepiandrosterone (DHEA).
- Endocrine regulation of calcium and phosphorus metabolism
Physiological role of calcium and phosphorus. Distribution and metabolism. Regulation of blood levels of calcium and phosphorus. Vitamin D, parathyroid hormone and calcitonin. Integrated regulation of calcium and phosphorus metabolism.
- Blood glucose control
Pancreatic islet hormones: insulin, glucagon. Effects on glucose, lipid and protein metabolism. Mutual and complementary interactions of pancreatic hormones.
- The adrenal medulla
Catecholamines and adrenergic receptors. Biological effects
Recommended Bibliography Fondamenti di Fisiologia Umana; L. Shervood, Casa Editrice: Piccin
FISIOLOGIA; C.L. Stanfield, Casa Editrice: EdiSES
Teaching Methods
Evaluation methods Verification of learning:
Depending on the training needs, ongoing tests may be done to detect the effectiveness of learning and teaching processes.
The final test consists of an oral discussion at the end of the course, in which the student must prove that he/she has learned the topics of the course program. The final verification can be sustained in one of the date present in the calendar after acquisition of presence.
The oral discussion focuses on a series of topics in which the student must demonstrate:
a sufficient but incomplete basic knowledge (vote 18-22/30),
a discreet knowledge with the ability to clearly illustrate the topics (23-25/30),
good ability to illustrate the subjects with properties of language (26-28/30),
excellent knowledge of the matter moving easily from one subject to another contextualizing any interconnections and/or differences (28-30/30).
The laude is reserved to those who also show particular interest and knowledge of the functional aspects of the professionalizing sector, with high communication skills and autonomous learning.
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