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Course Sheet Academic Year of enrolment:
Professor and Collaborators:
Hours of classroom activity:
Prerequisites:
knowledge of cellular and molecular biology, histology and biochemistry, acquired in the curricular courses and the.prerequisites required by the core curriculum of CdS
Objectives
Contents Etiology, Pathogenesis, homeostasis.
Cell adaptations and death.
Immunology and immunopathology
Inflammation
Oncology
Extended Syllabus General concept of health, disease and homeostasis. Intrinsic and extrinsic pathogenic factors. The environment as a cause of illness: pathology from physical, chemical and biological agents. Radiation disorders, immediate and late effects; electric currents, high and low temperatures: heat stroke, burns; freezing. Trauma disorders.
-Cellular adaptation: hypertrophy, hyperplasia, atrophy, aplasia, hypoplasia, metaplasia, dysplasia, anaplasia.Cell death. Apoptosis. Characteristics and phases of necrosis. Types of coagulative necrosis, colliquative, caseous, fibrinoid).
-Inflammation. Angioflogosis: phases and evolution (vascular changes, cellular events, chemical mediators). Exudate. Histoflogosis: phases and evolution. Granulomas. Systemic manifestations of inflammation. Regeneration, repair (granulation tissue, scar tissue) and wound healing.
-Immunology and Immunopathology. Non-specific and specific immunity. Mechanisms of the humoral and cell-mediated response (antibodies, antigens of the major histocompatibility complex, complement). Hypersensitivity reactions of type I, II, III and IV and related diseases.
-Oncology. Characteristics of benign and malignant neoplasms. Classification criteria for neoplasms. Definition of oncogenes and tumor suppressor genes. Tumor growth biology: cell differentiation, tumor progression, invasiveness and metastasis.
Environmental carcinogenesis. Starting and promoting agents. Phases of carcinogenesis.
Recommended Bibliography Pontieri G.M.: Patologia generale per i C.d.L. in professioni sanitarie. Piccin
Teaching Methods Knowledge will be acquired by single-issue lessons on all the topics of the course, with projection and discussion of illustrative slides. During the lessons there will be moments of discussion on specific topics to facilitate the understanding of the topics and the development of links between the topics. The learning of some issues can also be implemented by consulting texts provided by the teacher
Evaluation methods Verification of learning:
The verification of learning will be done by oral examination. It consists of an interview with the teacher. The interview is aimed at evaluating the student in the knowledge of the main concepts represented in the course objectives of the course; in the ability to use appropriate terminology; in the ability of critical synthesis of the topics dealt with also through the deepening in the recommended text.
At the end of the test, the teacher will formulate an opinion expressed in voting ranges and in marks out of thirty. The recording of the tests takes place through an electronic procedure in accordance with the methods indicated in Article 29 of the Administrative Careers Regulation.
Rated 30 - 30 cum laude: Excellent knowledge and understanding of the topics, reasoning skills and logical integration of the acquired knowledge, strong aptitude to make connections between different topics; excellent synthesis skills e. The student, who has achieved this evaluation, demonstrates autonomy of judgment, high communication skills and autonomous learning skills, will be offered praise.
Rating 27 - 29: Good knowledge and understanding of the topics with marginal and not serious gaps. Good ability to integrate logic and judgment. Mastery of scientific language;
Rating 23 - 26: Fair knowledge and understanding of the topics moderated in depth and, some gaps, in the ability to integrate and apply knowledge. significant mastery of scientific language
Rating 20 - 22: Knowledge and understanding of the fully sufficient arguments, little in-depth analysis, obvious gaps, which are reflected in a reduced capacity for integration, logic and application. Acceptable mastery of scientific language
Rating 18 - 19: Knowledge and understanding of the superficial arguments and with serious and obvious gaps. Sufficient knowledge to sustain a coherent dialogue but with poor integrative and applicative skills, but which also allow the passing of the exam.
Contacts/More Information The frequency at the lessons is mandatory and the final exam can be supported upon the acquisition of the frequency signature and in compliance with the prerequisites. As reported in the study plan.
The teacher is available for clarification to the students, in the time of receipt, by appointment.
From Monday to Friday dal lunedì al 10.00- 12.00
N.P.D., edificio C, III livello, tel. al 0871 3554029 mail:mreale@unich.it