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MICROBIOLOGY AND CLINICAL MICROBIOLOGY Course Sheet Academic Year of enrolment:
Degree:
Course of 1st Cycle Degree in NURSING
Disciplinary Sector:
Microbiology and Clinical Microbiology
Professor and Collaborators:
Hours of classroom activity:
Prerequisites:
Those indicated in the Academic Regulations
Objectives
Contents - Organization, structure and metabolism of the bacterial cell
- Pathogenicity of bacteria
- Infection control: sterilization, disinfection, and antibiotic therapy
- Laboratory diagnosis of infectious diseases
- Structure, biological cycle, and pathogenicity of fungi
- Structure, biological cycle, and pathogenicity of viruses
- Nosocomial infections: typology and control
Extended Syllabus Evolution of microorganisms and their classification.
Form and structure of the bacterial cell.
Bacterial reproduction; the production of spores: structure, sporogenesis, germination.
Microbial growth: culture media.
Bacterial metabolism: energy production, bacterial nutrition.
Pathogenic bacterial action: bacterial multiplication in vivo and toxigenicity.
Antimicrobial agents: mechanism of action, resistance to chemoantibiotics, antibiogram.
Sterilization and disinfection.
Description and pathogenesis of the main bacteria of medical interest (staphylococci, streptococci, Neisseriaceae, Enterobacteriaceae, M. tuberculosis).
Structure of metabolism and reproduction of the fungal cell.
Pathogenic action of the fungi.
Antifungal antibiotics.
Description and pathogenesis of the main fungi of medical interest (Candida, Aspergillus, dimorphic fungi).
Structure and chemical composition of viruses: viral proteins, viral nucleic acid, lipid envelope, virus glycoproteins. Classification criteria.
Mode of transmission of viruses.
Viral replication: mode of penetration, replication of the genome and synthesis of viral components, modality of viral progeny release.
Pathogenesis of viral infection: entry route, virus spread, cell damage, disease, recovery from infection.
Antiviral drugs.
General principles of virological diagnostics: methods for the identification of the viral genome, of proteins, of antibodies against the virus.
Description and pathogenesis of the main viruses of medical interest (HIV, hepatic viruses, CMV)
Nosocomial infections.
Recommended Bibliography - Castagliuolo I, et al: Principi di microbiologia clinica per le scienze infermieristiche; Piccin ed.
- De Grazia S, et al: Microbiologia e Microbiologia clinica; Pearson ed.
- Harvey RA, et al: Le basi della microbiologia; Zanichelli ed.
It will be provided additional teaching materials (lecture slides, recommended readings, videos, animations, web pages, etc.) available in the Teaching Teams channel to support and integrate the text.
Teaching Methods
Evaluation methods Verification of learning:
Interview to verify readiness in the subject area of the Integrated Course
Contacts/More Information Office hours for Students: from Monday to Friday, by appointment to be arranged by telephone (0871-3554812) or e-mail (gdibonaventura@unich.it )