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PHARMACOLOGY AND THERAPEUTICS Course Sheet Academic Year of enrolment:
Degree:
Course of 1st Cycle Degree in NURSING
Professor and Collaborators:
Hours of classroom activity:
Prerequisites:
The student must have basic knowledge of biology, biochemistry, anatomy and physiology.
Objectives
Contents The course includes two sections:
1) General pharmacology: this section describes the principles that underlie the human-drug interactions and that in turn are divided into two chapters, one related to Pharmacokinetics (the effects that the body has on drugs) and the other one on Pharmacodynamics (the cellular and molecular mechanisms that underlie the therapeutic, unwanted and toxic effects of drugs).
2) Special Pharmacology and therapy: this section describes the characteristics of the single classes of drugs (in particular those of the most common use in hospital settings).
Extended Syllabus PRINCIPLES OF GENERAL PHARMACOLOGY: definition of drug; generic drugs and medicinal specialties; overview of pharmacovigilance.
Pharmacokinetic elements: main routes of drug administration (outline of the main pharmaceutical forms and the correct administration of drugs); absorption, distribution, biotransformation and excretion of drugs; bioavailability; therapeutic range; plasma half-life; dose-effect curves (DE50, DL50, DT50); therapeutic index.
Principles of pharmacogenetics and variability of the pharmacological response.
Elements of Pharmacodynamics: drug-receptor interactions; main receptor classes; main signal transduction pathways; receptor agonists and antagonists; definition of power and maximum efficacy of a drug; receptor desensitization, upregulation, and downregulation.
PRINCIPLES OF SPECIAL PHARMACOLOGY
Pharmacological therapy of inflammation. Glucocorticoids and non-steroidal anti-inflammatory drugs (NSAIDs).
Drugs used in the treatment of bronchial asthma (essential lines on the most common drugs).
Drugs of more common use for the control of gastric acidity and for the treatment of peptic ulcer.
Drugs used in the treatment of arterial hypertension (essential lines on drugs of most common use).
Drugs used in the treatment of heart failure (essential lines on drugs of most common use).
Drugs active on the central nervous system with particular reference to the use of benzodiazepines
Antibacterial chemotherapy: Classification of antimicrobial drugs. Factors that determine the susceptibility and resistance of microorganisms to the most common antimicrobial drugs (Penicillins, Cephalosporins, Macrolides, Fluoroquinolones).
Recommended Bibliography Farmacologia -H.P. Rang, M.M. Dale, J.M. Ritter, P.K. Moore, Casa Editrice Ambrosiana, (ultima edizione).
For further information:“Fondamenti di farmacologia per infermieri” Clayton, Stock (ultima edizione)
Le basi della Farmacologia, 3rd edition, Zanichelli
Any additional materials will be made available by the teacher to supplement the recommended texts and uploaded to the dedicated website.
Teaching Methods The teaching is divided into lectures whose purpose is to transmit concepts, information and schemes.
Evaluation methods Verification of learning:
EVALUATION METHOD
Type of exam:
oral
The evaluation method consists of oral examination and the topics under examination will reflect those discussed during the lessons and present in the program.
At least one question will focus on topics of general pharmacology, one on topics of special pharmacology and one on topics of pharmaceutical botany.
The evaluation will be based on the knowledge of the topics covered by the exam questions and the student's logical-argumentative skills. For the purposes of the evaluation, the quality of the oral presentation will also be taken into consideration with particular reference to the competence in the use of the specialized lexicon.
If the teacher is not able to be present a test of 15 multiple choice questions (only one right) will be administered to the students.
The final grade is calculated as the average of the individual modules that, together with that of Pharmacology and Pharmaceutical Botany, are included in the integrated course.
The examination procedure and its evaluation are indicated by the teacher at the beginning of the lessons.
Evaluation:
Rating in thirtieths
Contacts/More Information Student Reception
Every Friday from 11 am to 1 pm at the CAST, Campus Universitario, Via Luigi Polacchi 11, 66013 Chieti Scalo. Tel 0871-541471