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BIOLOGY, ANATOMY AND HISTOLOGY Integrated educational activity
Course Sheet Academic Year of enrolment:
Hours of classroom activity:
Objectives
Contents Applied Biology
describe the organization of the cells;
- illustrate the structure of biological membranes and cell-environment interactions;
- describe the processes of mitosis, meiosis, phase duration and cell cycle regulation;
- as part of the structure of Nucleic Acids, illustrate the general characteristics of DNA. Describe the flow of genetic information from one cellular generation to another and describe the replication and repair of DNA. Describe the various levels of DNA organization in the cell. Illustrate the organization of the genome and extracellular DNA;
- to illustrate the general characteristics of the RNA knowing how to describe the flow of information within the cell, demonstrating to have understood the mechanisms of Transcription, of the Genetic Code, of the Protein Synthesis;
- regulation of gene expression in prokaryotes and eukaryotes.
- asexual and sexual reproduction. Spermatogenesis. Oogenesis. Fertilization
Human Anatomy
Starting from the INTRODUCTION TO SPLANCNOLOGY, the module deals with the study of the apparatuses and systems that make up the human body, with attention to the localization and relationships that the organs that make it take between them and with the surrounding structures hinting their functions.
Histology
Course contents provide the integrated knowledge of structural and ultrastructural morphology of different human tissues.
Extended Syllabus Applied Biology
Nucleic acids - Cell organization: - Cell theory - Cell organization and dimensions - Cell study methods - Cells
prokaryotic and eukaryotic - Cell membranes - The cell nucleus - The cytoplasmic organelles - The cytoskeleton - The cellular coatings - The biological membranes: - The structure of biological membranes - The passage of materials through biological membranes - Passive transport - Active transport - Exocytosis and endocytosis - Cellular junctions - Cellular communication: - Cell signaling: an overview - Reception - Signal transduction - Signal responses - The evolution of cellular communication - Cell energetic processes: - Biological work - The laws of thermodynamics - Energy and metabolism - ATP, energy currency of the cell - The transfer of energy in redox rations - The transformation enzymes of aerobiosis and cellular anaerobiosis: - Redox reaction - The four stages of aerobic respiration - Anaerobic respiration and fermentation-The structure of the chromosomes and processes of mitosis and meiosis: - Eukaryotic chromosomes, The cell cycle and mitosis - The regulation of the cell cycle - Sexual reproduction and meiosis - The structure and replication of DNA: - The proof that DNA is the hereditary material - The structure of DNA - The replication of DNA - Gene expression: - The discovery of the gene-protein relationship- The transcription- The translation- The fraction of genetics under examination- Mutations-The mechanisms of gene regulation: - Gene regulation in bacteria and eukaryotes- - Viruses - Viroids and prions - The prokaryotes - The two prokaryotic domains - the asexual reproduction - spermatogenesis, ovogenesis, the fecundation
Human Anatomy
Central nervous system
In a general manner: systematic, topographic, clinical radiological anatomy Spinal cord. Encephalous (brainstem, cerebellum, diencephalon, telencephalon)
Peripheral nervous system
Sympathetic System: Orthosympathetic and Parasympathetic
Cardiocirculatory system
Heart: location and topography. Structure and function of the valves. Functional anatomy of the circulatory system: arteries, veins and capillaries. The small circulation and the great circulation. Aorta and its primary branches of division.
Lymphatic system:
general characteristics of the lymphatic circulation. Lymph node stations of the head, neck, thorax, upper limb and lower limb. Main lymphatic trunks. Lymph nodes. Spleen: form, position, relationships and structure.
Respiratory system
Nose, nasopharynx, larynx, trachea, bronchi and pulmonary parenchyma. Pleure and respiratory mechanics
Digestive system
Vestibule of the mouth, oral cavity, pharynx, esophagus and stomach. Small intestine (duodenum, jejunum and ileum), large intestine. Liver and biliary ways. Pancreas.
Urinary apparatus
Kidney, calyxes and renal pelvis. Ureters. Urinary bladder. Male and female urethra.
Male Genital System
Testicles. Spermatic ways. External genital organs.
Female Genital Apparatus
Ovary. Genital ways. External genital organs.
Endocrine system
Pituitary, Thyroid, Adrenal: in a general manner.
Histology
- Cell structure.
- Cellular organelles and cytoskeleton.
- Extracellular matrix.
- Cell junctions.
- Active and passive transport mechanisms.
- Epithelial tissue.
- Exocrine and endocrine glandular epithelial tissue.
- Connective tissues.
- Cartilaginous tissue.
- Bone tissue.
- Hemopoietic and lymphatic tissue.
- Muscle tissue.
- Nervous tissue.
- Tissue embryological development (I-III week of development): Fertilization; Segmentation; Gastrulation; Embryonic
Recommended Bibliography Applied Biology
Solomon et al, Biology, EdiSeS Editore, 2017
Human Anatomy
F.H. Martini . ANATOMIA UMANA. EdiSES
Histology
-Istologia per le lauree triennali e magistrail. Bani. Idelson-Gnocchi.
-Elementi di istologia e cenni di embriologia. Filippini. Piccin.
-Citologia ed Istologia. Dalle Donne. Edises.
-Junqueira istologia. Testo e atlante. Junqueira. Piccin.
Teaching Methods Frontal lessons stimulating interactivity through classroom discussion of the topics addressed.
Evaluation methods Verification of learning:
the multiple choice test is composed of 45 questions proportionally distributed for the 3 modules: applied biology 15, human anatomy 15 and histology 15. Essential requirement to pass the exam is to answer at least 50% of the questions of each single module . the vote is calculated by multiplying the number of correct answers for each individual module by two and calculating the weighted average. The questions are prepared by the teacher during the academic year of reference.
The outcome of the test is evaluated as a result of learning the specific training objectives. At the end of the test a judgment is formulated that can be summarized using bands of vote in thirtieths:
A) excellent knowledge and understanding of the subjects, reasoning skills and logical integration of the acquired knowledge and insertion in the context of a clinical application. Rating: 30/30.If at the same time the student demonstrates autonomy of judgment, high communication skills will be proposed with praise.
B) Good knowledge and understanding of the topics with some non-serious inaccuracies and with good capability for logical integration, judgment and application to clinical practice. Rating: 27-29 / 30
C) Discrete knowledge and understanding of the topics with some gaps in the ability to integrate and apply knowledge. Rating: 24-26 / 30
D) Knowledge and understanding of the arguments fully sufficient, although with some gaps, which are reflect in a reduced ability of integration and application. Rating: 21-23 / 30
E) Knowledge and understanding of the topics with obvious gaps. Just sufficient integrative and applicative skills of the concepts learned. Rating: 18-20 / 30
F) Knowledge and understanding of the topics with serious and obvious gaps, with limited integrative and applicative skills. Rating: Rejected To proceed to the weighted average the student must have passed all the modules in the same exam session