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Course Sheet Academic Year of enrolment:
Professor and Collaborators:
Hours of classroom activity:
Objectives
Contents -describe the organization of the cells;
- illustrate the structure of biological membranes and cell-environment interactions;
- describe the processes of mitosis, meiosis, phase duration and cell cycle regulation;
- as part of the structure of Nucleic Acids, illustrate the general characteristics of DNA. Describe the flow of genetic information from one cellular generation to another and describe the replication and repair of DNA. Describe the various levels of DNA organization in the cell. Illustrate the organization of the genome and extracellular DNA;
- to illustrate the general characteristics of the RNA knowing how to describe the flow of information within the cell, demonstrating to have understood the mechanisms of Transcription, of the Genetic Code, of the Protein Synthesis;
- regulation of gene expression in prokaryotes and eukaryotes.
- asexual and sexual reproduction. Spermatogenesis. Oogenesis. Fertilization
Extended Syllabus Nucleic acids - Cell organization: - Cell theory - Cell organization and dimensions - Cell study methods - Cells
prokaryotic and eukaryotic - Cell membranes - The cell nucleus - The cytoplasmic organelles - The cytoskeleton - The cellular coatings - The biological membranes: - The structure of biological membranes - The passage of materials through biological membranes - Passive transport - Active transport - Exocytosis and endocytosis - Cellular junctions - Cellular communication: - Cell signaling: an overview - Reception - Signal transduction - Signal responses - The evolution of cellular communication - Cell energetic processes: - Biological work - The laws of thermodynamics - Energy and metabolism - ATP, energy currency of the cell - The transfer of energy in redox rations - The transformation enzymes of aerobiosis and cellular anaerobiosis: - Redox reaction - The four stages of aerobic respiration - Anaerobic respiration and fermentation-The structure of the chromosomes and processes of mitosis and meiosis: - Eukaryotic chromosomes, The cell cycle and mitosis - The regulation of the cell cycle - Sexual reproduction and meiosis - The structure and replication of DNA: - The proof that DNA is the hereditary material - The structure of DNA - The replication of DNA - Gene expression: - The discovery of the gene-protein relationship- The transcription- The translation- The fraction of genetics under examination- Mutations-The mechanisms of gene regulation: - Gene regulation in bacteria and eukaryotes- - Viruses - Viroids and prions - The prokaryotes - The two prokaryotic domains - the asexual reproduction - spermatogenesis, ovogenesis, the fecundation
Recommended Bibliography Solomon et al, Biology, EdiSeS Editore, 2017
Teaching Methods Frontal lessons stimulating interactivity through classroom discussion of the topics addressed.
Evaluation methods Verification of learning:
The multiple choice test is composed of 45 questions proportionally distributed for the 3 modules: the module of applied biology is composed by 15 questions. Essential requirement to pass the exam is to answer at least 50% of the questions of each single module. The vote is calculated by multiplying the number of correct answers for each individual module by two and calculating the weighted average. The questions are prepared by the teacher during the academic year of reference.
The outcome of the test is evaluated as a result of learning the specific training objectives. At the end of the test a judgment is formulated that can be summarized using bands of vote in thirtieths:
A) excellent knowledge and understanding of the subjects, reasoning skills and logical integration of the acquired knowledge and insertion in the context of a clinical application. Rating: 30/30.If at the same time the student demonstrates autonomy of judgment, high communication skills will be proposed with praise.
B) Good knowledge and understanding of the topics with some non-serious inaccuracies and with good capability for logical integration, judgment and application to clinical practice. Rating: 27-29 / 30
C) Discrete knowledge and understanding of the topics with some gaps in the ability to integrate and apply knowledge. Rating: 24-26 / 30
D) Knowledge and understanding of the arguments fully sufficient, although with some gaps, which are reflect in a reduced ability of integration and application. Rating: 21-23 / 30
E) Knowledge and understanding of the topics with obvious gaps. Just sufficient integrative and applicative skills of the concepts learned. Rating: 18-20 / 30
F) Knowledge and understanding of the topics with serious and obvious gaps, with limited integrative and applicative skills. Rating: Rejected To proceed to the weighted average the student must have passed all the modules in the same exam session
Contacts/More Information Prof.ssa Assunta Pandolfi: University G. D'Annunzio, Edificio CAST (ex-CeSI-Met), Tel. 0871-541425 email: assunta.pandolfi@unich.it