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BIOLOGY OF CELLULAR DEGENERATION MECHANISMS Course Sheet Academic Year of enrolment:
Professor and Collaborators:
Hours of classroom activity:
Objectives
Contents -describe the organization of the cells;
- describe the biological macromolecules;
- illustrating the structure of biological membranes and cell-environment interactions;
- describe the processes of mitosis, meiosis, duration of the phases and regulation of the cell cycle;
- within the structure of the Nucleic Acids, to illustrate the general characteristics of the DNA. Describe the flow of genetic information from one cell generation to another and describe DNA replication and repair. Describe the various levels of DNA organization in the cell. To illustrate the organization of the genome and of the extracellular DNA;
- to illustrate the general characteristics of the RNA, knowing how to describe the flow of information within the cell, demonstrating that it understood the mechanisms of Transcription, of the Genetic Code, of the Protein Synthesis;
Extended Syllabus The chemistry of life (not in detail):
- Atoms and carbon molecules
- Carbohydrates
- Lipids
- Proteins
- Nucleic acids
The organization of the cell:
- Cell theory
- The organization and size of the cell
- Cell study methods
- Prokaryotic and eukaryotic cells
- The cell nucleus
- The cytoplasmic organelles provided with a membrane
- The cytoskeleton
- Cellular coatings
Biological membranes (not in detail):
- The structure of biological membranes
- The passage of materials through biological membranes
- Passive transport
- Active transport
- Exocytosis and endocytosis
- Cellular junctions
- Cellular signaling: an overview
The processes of aerobiosis and cellular anaerobiosis:
- Redox reaction
- The four stages of aerobic respiration
- The energy yield of nutrients other than glucose
- Anaerobic respiration and fermentation
The structure of the chromosomes and the processes of mitosis and meiosis (not in detail):
- Eukaryotic chromosomes
- The cell cycle and mitosis
- Stem cells and tissue homeostasis
- Cell cycle regulation
- Sexual reproduction and meiosis
DNA structure and replication (not in detail):
- Evidence showing that DNA is the hereditary material
- The structure of DNA
- DNA replication
The gene expression:
- The discovery of the gene-protein relationship
- Information flow from DNA to proteins: an overview
- The transcription
- Translation
Viruses and subviral agents:
- Status and structure of viruses
- Virus classification
- Viral replication
-Viruses and diseases
- Virus evolution
- Subviral agents
Bacteria and archaeobacteria:
-The structure and reproduction
Recommended Bibliography Solomon et al, Biology, EdiSeS Editore, VII edizione Napoli
Teaching Methods
Evaluation methods Verification of learning:
The evaluation of the student includes an oral exam, which will serve to demonstrate the knowledge of the program carried out, the logic followed by the student in the resolution of the questions asked and the adequacy of the language, at the end a vote will be attributed expressed in thirtieths.
Contacts/More Information Prof. Assunta Pandolfi: University G. D'Annunzio, CAST (ex-CeSI-Met)
Tel. 0871-541425 email: assunta.pandolfi@unich.it
Experimental Biology: Prof. Assunta Pandolfi CAST, Room 421, Tel 0871-541425 email: assunta.pandolfi@unich.it
The prof. meets the students EVERY WEDNESDAY FROM 11.30 TO 13.30