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Course Sheet Academic Year of enrolment:
Disciplinary Sector:
Laboratory Medicine Techniques
Professor and Collaborators:
Hours of classroom activity:
Prerequisites:
Biochemistry and physiology are preparatory teachings for this teaching
Objectives Contents To know the genetic characteristics of some types of tumors, with particular regard to those of the reproductive system
Extended Syllabus Molecular diagnostics of hereditary tumors.
- Inflammatory diseases and carcinomas of the uterine cervix.
- Molecular and clinical bases of endometrial tumors. Endometrial carcinoma and HNPCC.
Hints on therapy.
- Molecular and clinical bases of breast and ovarian tumors. Eligibility criteria for genetic testing. Treatment of breast cancer and ovary. Hints on molecular therapy.
- Molecular and clinical bases of hereditary tumors of the colon: Lynch syndrome -HNPCC, familial adenomatous polyposis of the colon-FAP, adenomatous polyposis of the colon associated with the MUTYH gene -MAP.
- Molecular basis of familial gastric cancer: intestinal type and Diffuse type. Hints of therapy.
- Molecular and clinical bases of pancreatic tumors, PanIN classification, outline of molecular therapy.
- Overview of instrumental diagnostics (DHPLC, automatic sequencer)
Recommended Bibliography Reading materials provided by the teacher
Teaching Methods The course consists of lessons at compulsory attendance
Evaluation methods Verification of learning:
COURSE GRADE DETERMINATION
Contacts/More Information Prof.ssa Maria Cristina Curia
Tel: 0871-3554103 E-mail mariacristina.curia@unich.it
. Student reception hours: from Monday to Friday from 11 to 12 at the Nuovo Polo Didattico, Building C, III floor
